Based on https://chromeisbad.com/, I removed Chrome and Keystone from several of my Apple computers. The performance is somewhat better on an older iMac. While freeing up space isn't the main intention, this freed up 20G of space where it was almost full.
Since I prefer the command line, this generates a list of directories:
ls -adl /Library/* /Library/LaunchAgents/* /Library/LaunchDaemons/* /Library/Application\ Support/* /Library/Caches/* /Library/Preferences/* | grep -i -e google -e keystone ls -adl ~/Library/* ~/Library/LaunchAgents/* ~/Library/Application\ Support/* ~/Library/Caches/* ~/Library/Preferences/* | grep -i -e google -e keystone